Telomeres are essential to preserve the integrity of the genome. Critically short telomeres lead to replicative cell senescence and chromosomal instability and may thereby increase cancer risk.
A telomere is a region of repetitive DNA at the end of a chromosome, which protects the end of the chromosome from deterioration. Its name is derived from the Greek nouns telos (τἐλος) “end” and merοs (μέρος, root: μερ-) “part”.
Telomerase is an enzyme that adds DNA sequence repeats (“TTAGGG” in all vertebrates) to the 3′ end of DNA strands in the telomere regions, which are found at the ends of eukaryotic chromosomes. The telomeres contain condensed DNA material, giving stability to the chromosomes.
Telomeres have been compared with the plastic tips on shoelaces because they prevent chromosome ends from fraying and sticking to each other, which would scramble an organism’s genetic information to cause cancer, other diseases or death.
This article will teach you the basics of telomeres and telomerase. It will also introduce you to the potential applications of current telomerase research.
An unusual enzyme called telomerase acts on parts of chromosomes known as telomeres. The enzyme has recently been found in many human tumors and is being eyed as a new target for cancer therapy
Astragalus has been used in traditional Chinese medicine for centuries. Its main use has been to boost the body’s immune system. But it also has been used to treat other conditions, including heart disease. That raises the question of exactly what heart benefits astragalus might offer. And if it does offer heart benefits, are there side effects you should know about? Who should and who shouldn’t use astragalus?
Astragalus propinquus is a flowering plant in the family Fabaceae. It is one of the 50 fundamental herbs used in traditional Chinese medicine. It is a perennial plant and it is not listed as being threatened.